hematopoiesis相关论文
Mapping Human Pluripotent Stem Cell-derived Erythroid Differentiation by Single-cell Transcriptome A
There is an imbalance between the supply and demand of functional red blood cells (RBCs) in clinical appli-cations. This......
Panaxdiol Saponins Component Promotes Hematopoiesis and Modulates T Lymphocyte Dysregulation in Apla
Objective:To investigate the potential efficacy of panaxadiol saponins component (PDS-C) in the treatment of aplastic an......
目的 DEK is a highly conserved chromatin-bound protein and originally discovered fused to the nucleoproin CAN in a subse......
Dysregulation of ribosome biogenesis causes human diseases, such as Diamond-Blackfan anemia, 5q minus syndrome and bone ......
Background: Dragons blood is a Chinese traditional herb, which was shown to have certain anti-radiation effects due to t......
Inducible overexpression of GATA-2 on human pluripotent stem cells promotes the generation and expan
GATA-2 show dynamic changes in the expression profiles during hematopoiesis,which particularly expresses high on hematop......
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Dynamic regulation of GATA2 in fate determination in hematopoiesis: possible approach to hPSC-derive
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Ltv1 plays an essential and P53-independent role in zebrafish definitive hematopoiesis and digestive
Ribosome biogenesis is a ubiquitous and essential process in cells.Disruptions in ribosome biogenesis are deleteriou......
Functionally mature blood cells derived from human pluripotent stem cellsPossible rule in future cli
The establishment of human embryonic stem cell (hESC) and induced pluripotent stem cells (hiPSC) has greatly expande......
目的FL(Flt3 ligand)是一种作用于早期造血细胞的生长因子,为进一步研究FL水平与辐射所致造血损伤的相关性,观察了小鼠受γ射线全......
Hematopoietic stem cells (HSCs), which are localized in the bone marrow of adult mammals, come from hematopoietic endoth......
Objective: To investigate the effect of bone morphogenetic proteins (BMPs) on hematopoietic injury of acute radiation si......
Rheb为GTP结合蛋白,可调控细胞的生长、增殖、凋亡、存活以及自噬等细胞的基本生命活动,其与结节性硬化症和某些肿瘤相关。 Rheb可调......
目的 观察叶酸缺乏对斑马鱼胚胎造血干细胞发育的干扰作用以及对胚胎造血区凋亡的影响,初步探讨叶酸缺乏导致血液生成异常的机制.......
Cocultivation of umbilical cord blood CD34+ cells with retro-transduced hMSCs leads to effective amp
AIM: To establish a novel coculture system for ex vivo expansion of umbilical cord blood(UCB) hematopoietic progenitors ......
Multiple myeloma (MM) is a plasma cell cancer characterized by sustained endoplasmic reticulum (ER) stress and unfolded ......
In vivo imaging is crucial for developmental biology and can further help to follow cell development/differentiation in ......
The AML1-ETO fusion transcription factor is generated by the t(8;21) translocation,which is present in approximately 4%-1......
,Toll-like receptor signaling in hematopoietic homeostasis and the pathogenesis of hematologic disea
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Recent studies have suggested that prostaglandin (PG) E2 (PGE2) and the prostaglandin pathway are essential for hematopo......
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,The immunologic and hematopoietic profiles of mesenchymal stem cells derived from different section
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Toll样受体(TLR)是近年来发现的一类天然免疫受体,在天然免疫及获得性免疫过程中均发挥非常重要的作用.对TLR的深入研究表明,TLIRs......
Glia Maturation Factor Gamma (GMFG): A Cytokine-Responsive Protein During Hematopoietic Lineage Deve
本文通过对荣华二采区10...
目的 探讨雪莲培养细胞提取物对辐射所致小鼠造血功能损伤的影响. 方法 100只昆明种雄性小鼠,采用数字随机表法平均分为空白对照组......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Kzp Regulates the Transcription of gata2 and pu.1 during Primitive Hematopoiesis in Zebrafish Embryo
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Leukemic stromal hematopoietic microenvironment negatively regulates the normal hematopoiesis in mou
Background and Objective: Leukemic microenvironment has a major role in the progression of leukemia. Leukemic cells can ......
目的探讨吸入式甲醛暴露对小鼠骨髓组织中转录因子GATA-2和CCAAT/增强子结合蛋白(C/EBPα)在mRNA以及蛋白表达水平的影响。方法将2......
To assess the mechanisms of modest hypothermia(MH) and its effects on cellular radiation response, a model of anesthesia......
转录因子GATA-2是GATA家族的一成员,以其锌指结构结合于[(T/A(GATA)A/G]的共同DNA序列结构.近期,通过敲除小鼠GATA-2基因的实验证......
骨髓间充质干细胞(MSC)以其多向向中胚层起源细胞分化潜能及自我更新的干细胞特征,成为骨髓造血微环境中重要的构成组分及前体成分......
Leukemic stromal hematopoietic microenvironment negatively regulates the normal hematopoiesis in mou
Background and Objective: Leukemic microenvironment has a major role in the progression of leukemia.Leukemic cells can i......
目的探讨成骨细胞对放射损伤小鼠骨髓造血系统及血管恢复的影响。方法取18只雄性BALB/c小鼠股骨制备成骨细胞,其余42只小鼠随机分成......
目的探讨重组人甲状旁腺素(parathyroid hormone,PTH)对辐射所致小鼠造血功能损伤的防护作用。方法雄性C57小鼠60只,经^60Coγ射线照射......
Cocultivation of umbilical cord blood CD34+ cells with retro-transduced hMSCs leads to effective amp
AIM: To establish a novel coculture system for ex vivo expansion of umbilical cord blood(UCB) hematopoietic progenitors ......
Rheb为GTP结合蛋白,可调控细胞的生长、增殖、凋亡、存活以及自噬等细胞的基本生命活动,其与结节性硬化症和某些肿瘤相关。 Rheb可调......
Glia Maturation Factor Gamma (GMFG): A Cytokine-Responsive Protein During Hematopoietic Lineage Deve
Human hematopoiesis was evaluated using the techniques of controlled stem cell differentiation, two-dimensional gel elec......
Acquired aplastic anemia:Is bystander insult to autologous hematopoiesis driven by immune surveillan
We previously reported a serendipitous finding from a patient with refractory severe aplastic anemia who had gotten an u......
为了探讨甲醛对小鼠造血功能的影响,将昆明小鼠30只随机分为5组,分别为低、中、高浓度甲醛组,盐酸苯肼试验组和空白对照组,试验期......
目的:观察黄芪注射液对放化疗因素所致骨髓抑制性贫血小鼠造血的影响.方法:采用Co60照射加注射环磷酰胺、氯霉素复合造模建立贫血......
本文首次报道采用微量甲基纤维素体外培养法,培养出小鼠骨髓巨核祖细胞。1u/ml促红细胞生成素、5%植物血凝素条件培养液及2.5%美州商......